![]() ![]() Facial flushing may occur a few hours postinjection and is present in up to 15 percent of patients. Of these women, 137 (70 percent) were premenopausal and 60 (30 percent) were postmenopausal.įacial flushing after steroid injections is more common in women than in men. In a comprehensive paired observational cohort study of 6,926 women who had not had hysterectomies, 197 (2.8 percent) had abnormal vaginal bleeding after the injection. Medical professionals should inform female patients that abnormal menstrual bleeding is a potential side effect for the procedure.īoth intra-articular and epidural corticosteroid injections have resulted in postinjection abnormal vaginal bleeding. TA may interfere with female sex hormones, causing disturbances in levels that manifest as irregular menstruation. These disturbances ranged from the timing of menses (earlier or later than expected) to more loss of blood and longer duration of menstruation. In one study, 51 percent of women who had received either an intra-articular, epidural, or soft-tissue TA injection with a mean dose of 24 mg reported a disturbance in menstrual pattern. Previous literature reports suggest that triamcinolone acetonide (TA) injections may cause a disturbance in female sex hormones, including luteinizing hormone and progesterone. Several review articles and many case reports identify abnormal menstruation as a side effect of intra-articular and epidural corticosteroid injections. This article discusses these potential side effects to increase awareness of their existence among orthopaedic surgeons. Furthermore, female patients may face additional sex-related adverse effects, most notably abnormal menstruation. Commonly discussed side effects include postinjection flare, skin changes (hypopigmentation), fatty atrophy, infection, facial flushing/allergic reaction, tendon damage, and transient increase in blood glucose. By reducing vascular permeability and inhibiting the production and accumulation of inflammatory mediators such as prostaglandins and leukotrienes, corticosteroids are clinically effective in increasing joint mobility, reducing joint inflammation, and decreasing erythema, swelling, and acute pain.Īlthough corticosteroid injections are simple to perform and the risk-benefit ratio is highly favorable, some adverse side effects are not unusual. Corticosteroids are often used to treat knee and shoulder osteoarthritis, rotator cuff tendinopathy, adhesive capsulitis, and acute inflammation. Do not use this medication without telling your doctor if you are breast-feeding a baby.Corticosteroid injections are a nonsurgical treatment modality, frequently used when other conservative treatments are ineffective. ![]() It is not known whether sodium chloride passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sodium chloride will harm an unborn baby. if you are allergic to any foods or drugs orįDA pregnancy category C.if you are pregnant and you have high blood pressure and fluid retention (also called preeclampsia).fluid retention (especially swelling in your ankles or feet ). ![]() a buildup of fluid around your lungs (also called pleural effusion). ![]() To make sure you can safely take sodium chloride, tell your doctor if you have any of these other conditions: You should not take sodium chloride if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood. ![]()
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